Howard Florey

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Howard Florey was the first Australian to win the Nobel Prize for Physiology or Medicine. He shared the 145 award with the German refugee chemist Ernst Chain and the Scottish microbiologist Alexander Fleming. Working together at Oxford University, Florey and Chain built a research team that transformed penicillin (discovered by Fleming in 1) from a laboratory curiosity into a widely available drug. Penicillin is one of the most efficient remedies ever discovered, and in the 140s its effects seemed almost miraculous. It revolutionized medicine, allowing once lethal infections, pneumonia, diphtheria, syphilis, meningitis, gas gangrene--to be cured. For infections that were resistant to penicillin, other antibiotics were soon found, including cephalosporin, which was also developed by the Oxford group. Florey was born in Adelaide to a wealthy family. Rather than enter his fathers shoe-making business, he resolved to study medicine, and in 11 won a Rhodes scholarship to Oxford University. In the mid-10s, he became intrigued by the problem of extracting pure penicillin from the Penicillium mold without destroying its potency. He later assembled a multidisciplinary team--including his wife Ethel to work on manufacturing the drug. The technical difficulties of carrying out such a project in wartime Britain were enormous, and at first the team struggled to produce enough penicillin to cure a few infected mice. The amounts available to treat the earliest patients were so limited that the researchers concentrated the drug back from urine, then reinjected it. But (thanks in part to collaboration with well-funded U.S. researchers) by the time of the D-Day landings in 144, penicillin was available in sufficient quantities to save the lives of many wounded Allied and German soldiers. In his approach to practical science, Florey was a true experimentalist, and is credited with establishing the nexus between physiology (normal function) and pathology (disease) that defines the discipline of experimental pathology.

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The Nobel and other accolades gave Florey great influence, which he used well. He visited Australia often, and his efforts were central to the establishment of the Australian National University as a postgraduate research university, a visionary idea for its time. Florey assumed responsibility for the initial phase of the ANUs John Curtin School of Medical Research, contributing greatly to the recruitment of a stellar group of founding professors. Though he continued living in England, he was chancellor of the ANU (making annual trips to Canberra), when he died at age 6 from cardiovascular disease. A typical Australian stoic, he suffered angina in silence for many years. Today, coronary bypass surgery would probably have given him a decade more of productive life.Florey was a familiar figure to Australians of his time, but the 100th anniversary of his birth, in 18, attracted little public interest, even in his home town of Adelaide. When I spoke there at a well-advertised event in his honor, the Crows football team were on a winning streak and the press seemed terminally obsessed with Sir Donald Bradmans 0th birthday. Australia has not, so far, been looked on as a land of opportunity for the intellectual, Florey said in 158. That is changing, but young Australians need to be reminded that their country has produced great achievers in science, the arts and the world of ideas. A sophisticated society can support a broad pantheon of heroes.Peter Doherty and Rolf Zinkernagel won the 16 Nobel Prize for Physiology or Medicine for their work on viral infections and immunity, carried out at the John Curtin School of Medical Research.BORN Sept. 4, 188, in Malvern, Adelaide1 Attends Oxford University on a Rhodes scholarship15 Becomes Professor of Pathology at Oxford14 His department publishes Antibiotics160 Becomes first Australian president of the Royal Society165 Becomes life peer as Baron Florey of Adelaide and MarstonDIED Feb. 1, 168, in OxfordFlorey gathered a team of scientists at Oxford University in Britain in the 10s, when working together on scientific discoveries as a group was not at all common.His team commenced a careful investigation of the properties of anti-bacterial substances that are produced by mould. One member of the team, Ernst Chain, found an article about Alexander Flemings work while flicking through a medical journal, and this prompted them to begin looking at penicillin. Individual members of the group concentrated their attention on areas in which they had the most knowledge, but they often met to exchange ideas. Chain worked on purifying penicillin with Edward Abraham. Norman Heatley improvised methods for extracting penicillin using ether and bedpans (see penicillin production below). A. D. Gardner and Jena Orr-Ewing studied how penicillin reacted with other organisms. Howard Florey looked with Margaret Jennings at the impact of penicillin on animals. Ethel Florey later worked with her husband on clinical trials of penicillin. In May, 140 they performed one of the most important medical experiments in history. The work was so urgent that they came in to begin the experiment on the weekend, and on Saturday 5 May, Floreys team tested penicillin on eight mice injected with a lethal dose of streptococci bacteria. Four of the mice were treated with penicillin, while four were used as controls. By the next day, the treated mice had recovered and the untreated mice were dead. In the early days of World War II, the lives of eight mice may seem insignificant. But their rescue by penicillin led to the treatment of Allied soldiers as early as D-Day, in June 144, and probably influenced the outcome of the war. In 14 Florey travelled to North Africa to test the effects of penicillin on wounded soldiers. His trials were seen as a miracle. Instead of amputating wounded limbs or simply leave them to heal, he suggested soldiers wounds be cleaned and sewn up, and that the patients then be given penicillin. Thanks to Florey and his team, the drug was available to treat Allied troops by the end of World War II. It has since revolutionised medical science, saving millions of lives. Please note that this sample paper on Howard Florey is for your review only. In order to eliminate any of the plagiarism issues, it is highly recommended that you do not use it for you own writing purposes. In case you experience difficulties with writing a well structured and accurately composed paper on Howard Florey, we are here to assist you. Your cheap research papers on Howard Florey will be written from scratch, so you do not have to worry about its originality.

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Organizational Behavior – Application Paper -1 Applying Organizational Behavior concepts in the initial phases of team leading

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This paper talks about my current assignment at my work, which is to lead a team of 15 engineers to deliver a software product with a strict deadline of 10 months. Leading a large team with strict delivery deadlines is challenging. Issues such as making the team members align to my thoughts about how the project has to be executed, getting agreement on priorities and task allocations, etc. not only requires me to be technically strong but also requires me to have good organizational skills. The application of methods and techniques from Organizational Behavior is very helpful in such challenging management situations. The focus in this paper is on the team leading tasks involved in the initial stages of the project.The first and foremost task with my new responsibility of leading the team was to send a message to the members of the team about my general impression about the members. I wanted them to feel that I trust them to do their work and trust them to be responsible. This can be closely related to the contemporary view about employees versus the traditional theory which views employees as being lazy, and needs employees to be pushed to do their work, etc. I let each of the team members to know that they will be given adequate training, support , and encouragement and will be rewarded well for success. Developing a good project plan is a very important task. Active participation from all team members in preparing the project plan is very important. Soliciting the active participation of team members in preparing the project plan helped me to gain confidence of the team members, helped the team members to get a bigger picture of the project and also helped them to understand the phases in execution.

Identifying the training needs is an important task since strong technical skills of each of the team member is of vital importance for each team member to perform well. Another important task to increase efficiency is to identify technical skills that each of the team members possessed and to make use of these skills. Allotting the right task to each individual is of vital importance since this would save a lot of time in learning. These aspects are covered under knowledge management in organizational behavior. Knowledge Management is very important in technology companies as both proper training and proper utilization of existing skills will increase efficiency and productivity. For example, reusing an existing piece of software will not only save time in writing the software but will also decrease the chances of new bugs in the software.I also needed to establish clear guidelines to write quality software and code reviews. Code reviews involved peers reviewing each other's code. The exercise of these reviews is to give feedback to the team members on their quality of work. Enforcing discipline in terms of writing bug free, good quality software is important to the quality of the product and customer satisfaction. For example Letting the team know that delivering a piece of code without adequate testing would lead to warning the relevant team members. Team members were interested to know what norms I expected from them with respect to work timings, telecommuting, etc. I tried to set up a working relationship that will ensure a fair treatment to every one without any favoritism. For example The norm with respect to telecommuting is every team member is allowed to work from home once a week. A team member also could work from home when he or she has genuine issues such as childcare. Since software projects generally do not require people to be at the work place at all times, flexible timings with 40 hours of work per week gives a lot of flexibility to the team members to deal with personal situations such as dropping the child to school, etc. One mandatory requirement however is that I required every team member to attend weekly team meetings. The weekly team meetings are very helpful for each of the team members to know what others in the team are doing, share any issues technical or non-technical faced by the team, update project schedules and also the weekly meetings provide a platform for team members to express opinions freely.A one on one conversation with each team member helped me to understand to some extent the personality of each of the team member. Identifying and knowing about each person's personality helps to understand the behavior, what challenges each one can take in the team. For example, a couple of team members are more likely to handle stressful situations better than others. I was able to recognize weakness of one team member who had problems teaming up with others and has an arguing type of personality. The big five dimensions of personality Conscientiousness, Extraversion-Intraversion, Agreeableness, Emotional Stability, Openness to experience have been found to account for differences in the way people behave in organizations. Careful measures in early stages of the project are very important since it is relatively easy to set expectations and establish working relationships in the early stages of team formation. . Please note that this sample paper on Organizational Behavior – Application Paper -1 Applying Organizational Behavior concepts in the initial phases of team leading is for your review only. In order to eliminate any of the plagiarism issues, it is highly recommended that you do not use it for you own writing purposes. In case you experience difficulties with writing a well structured and accurately composed paper on Organizational Behavior – Application Paper -1 Applying Organizational Behavior concepts in the initial phases of team leading, we are here to assist you. Your cheap custom college paper on Organizational Behavior – Application Paper -1 Applying Organizational Behavior concepts in the initial phases of team leading will be written from scratch, so you do not have to worry about its originality.

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As You like it

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As You Like It The main themes of As You Like It ...As You Like It The main themes of As You Like It are the pastoral ideal and the ideal of romantic love. Forest of Aden is the primary setting where these themes develop. Nature serves as a refuge from society where we can find solutions to injustice and unhappiness. This play is a comedy and thus has a happy ending but it is not a fairy tail. Shakespeare highlights the difference between reality and illusion. Rosalind embodies the sensibility, the humor and the kind of love that leads to a happy, harmonious living. She brings the plot to a resolution when four contrasting romances end in marriage. The focus of the play is her romance with Orlando. Rosalind wants to find a lover without losing her sense of self in the process. Rosalind answers the questions about love, which arise during the play. She is a lovesick maiden and yet she remains an intelligent, witty, and strong character. Rosalind is also a good judge of character. She sees through Jaques seemingly deep thoughts and recognizes the wisdom of clown Touchstone. Furthermore, she cleverly uses her disguise to get to know Orlando and educate him about love. The meeting of Orlando and Rosalind is the most important event in Act 1 of the play; it is love at first sight. Celia and her cousin talk about falling in love just before the wrestling match. From henceforth I will, coz, and devise sports. Let me see, what think you of falling in love? Her words indicate that Rosalind is ready to face the danger of falling in love. She infers that her father would approve of Orlando because her father approved of his father Sir Rowland. Their meeting reveals a vulnerable side of the Rosalind as she gives him a chain, says, Gentleman, wear this for me and waits for him to continue the conversation. In Act Shakespeare draws parallels between Rosalinds relationship with Celia and Orlandos relationship with Adam. When Duke Fredrick banishes his niece from the court,

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Celia makes a quick decision to go to the Forest of Aden with her cousin and to look for her uncle. This illustrates the degree if love and loyalty between them. Orlandos elder brother Oliver denies him education. When Orlando is leaving for the forest Adam wants to go with him to serve and protect him. Master, go on, and I will follow thee To the last gasp with truth and loyalty... Yet fortune cannot recompense me better Than to die well and not my masters debtor. (.4. 70-75) Soon after entering the Forest of Arden Rosalind discovers love poems that Orlando hang on the trees. She loses self-control as she reads them one after another. When she finds out that Celia has seen Orlando she is very excited and cannot stop asking her questions, What did he when you thou sawst him? What said he? How looked he... (.. 18-0) For a brief period of time, she becomes a victim of infatuation like those she scorns. She is betrayed by something she feels and finds it difficult to admit the truth in love. Shakespeare thus illustrates that she is not ideal, that she has flaws like all other human being. Rosalinds clever idea to dress up as Ganymede enables her to have a double identity, which will give her the opportunity to test Orlandos love. Her disguise probably prevents their immediate marriage. I will speak to him like a saucy lackey and under that habit play the knave with him. (..-) She does not however merely play games, Rosalind she teaches Orlando how to love her. He must keep his promises and respect her thereby proving that his love is real. She takes a cynical view of romantic love to tease Orlando. Rosalind begins to tire of acting after the momentary drop of her guise when she faints at seeing Orlandos bloody handkerchief. When Orlando proves himself to Ganymede and saves the life of his brother Rosalind is ready to make a commitment to him. She does not dispose of her disguise until then because she realizes that only time will show if they are really in love. Time refines their passion for one another. Rosalind is a philosopher Rosalind like Jaque. Her practical love-filled perceptions of the world contrast with his cynical views. Jaque likes to disagree with everyone else. Both Orlando and Rosalind challenge his ideas. In the third act Jaque tried to persuade Orlando that loving Rosalind is not worth his while. Jaque. The worst fault you have is to be in love. Orlando. Tis a fault I will not change for your best virtue. I am weary of you. (.. 7-8) Rosalind tells Jaque that he is sad and melancholy because he chooses to stay detached from the real life she says Fear you have sold your own lands to see other mens... I had rather fool to make me merry than experience to make me sad. Thus Jaque loses in this brief exchange. Touchstone is the fool whom Rosalind would prefer to Jaque. She understands his wisdom You speakst wiser than thou art ware of. Touchstone tells her a story about being in love with a girl. He gave the girl something and said wear these for my sake, which are almost the same words that Rosalind said to Orlando in the beginning of the play. The love between Orlando and Rosalind is portrayed as superior to other romances, which are more earthy. Touchstone and Audreys romance represents physical passion. He wants to marry her out of church so that the marriage would be invalid. Silvius who is hopelessly in love with Pheobe, represents pastoral love The diversity of characters romantic sentiment creates a balance in the play and makes one appreciate their silliness, spirituality and extremities. Compared to Silvius silly infatuation, Orlandos is more of a courtly lovesickness. Rosalind outshines everyone else in the play with her intelligence, wit and depth of feeling. Her humanity and sense of fun make her the ideal romantic heroine. She seems to be centuries ahead of her time. She is a woman who is absolutely the master of her own destiny and she remains in control most of the time. Shakespeare has created an almost ideal heroine who brings the play to its conclusion. Please note that this sample paper on As You like it is for your review only. In order to eliminate any of the plagiarism issues, it is highly recommended that you do not use it for you own writing purposes. In case you experience difficulties with writing a well structured and accurately composed paper on As You like it, we are here to assist you. Your persuasive essay on As You like it will be written from scratch, so you do not have to worry about its originality.

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Montana 1948 EssayMaturity

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may come at any age and time in a person's life. One moment he or she may be a carefree child, and then suddenly realize that they have been transformed into a mature adult by a powerful and traumatic experience. An experience they will remember their whole lives. In To Kill a Mockingbird by Harper Lee, the adolescence of Jem and Scout is threatened one fateful night by a dangerous man bent on taking their lives. After this startling experience, they were never the same again. As a result, they rapidly matured into adults. Similarly, young David Hayden, the narrator of Montana 148 by Larry Watson, also encounters an equally traumatic event. He discovers that his uncle has been sexually assaulting Native American women in his town. This is a heavy burden for a twelve year old boy, especially since it reveals that his beloved Uncle Frank is the bad-guy. However, one discovers, as the novel develops, that David matures and grows in order to deal with this situation. He must come to understand what has happened and how the immoral actions of Frank will affect his family and its name. But most importantly, he must know that his integrity will be changed. He will learn shocking things that would mean nothing to a child, but everything to an adult. Larry Watson suggests that traumatic experiences transform children into adults. Therefore, disturbing experiences lead to changes of mind, growth in morals, and an emerging sense of adulthood. David changes his mind about Uncle Frank through the traumatic experiences regarding the discovery of Frank's secret actions. Uncle Frank used to be David's idol and David adored him. But that all changed when David's housekeeper and baby sitter, Marie Little Soldier, becomes violently ill and is in need of a doctor. Wes Hayden, David's father, calls his brother Frank, who is the town doctor, to come and see her. Strangely enough, Marie Little Soldier refuses to be alone in the room with Frank. Later on, Marie tells David's mother horrible things that Frank has been doing to Native American women. David's mother, Gail, tells Wes as David overhears. She says, 'Wesley, your brother has been raping these women. These girls. These Indian girls…' [David states] I was beginning already to think of Uncle Frank as a criminal…Charming, affable Uncle Frank was gone for good (47, 4). David always thought goodly of his uncle, until he heard these ghastly statements. All the attractiveness and appeal of Frank dissipated once David learned of his filthy behavior. David knew this information would change him forever. He takes another step toward adulthood by hearing and understanding what his uncle has done. David also knows that his opinion of Frank is changing. Young David Hayden grows in morals due to the shocking events of the summer of 148. Consequently, David learns a great lesson about morals from all the episodes that occur. Marie is found dead a few days after Frank goes in to see her. Frank claims she died of pneumonia. David's next door neighbor, Daisy McAuley, goes to their house to comfort Gail. Daisy treats David maternally and wants him to leave the scene of the crime. So she tell him to go over to her house and have a piece of pie. While he's there, David encounters the deputy sheriff, Len McAuley. Len is drunk and reveals the fact that he thought he saw Frank walking into David's house a little while before Marie was found dead. David discloses this and the fact that, he too, saw Frank. David confesses to his parents, …While I was sitting there I saw someone cutting across our backyard. There's a knothole you can see out of. I was pretty sure it was Uncle Frank. Then I got out and watched him go down the tracks. He was going toward town… (7). After receiving the shock of knowing his uncle is a fiend, David experiences a growth in morality. He chooses to tell his parents what he knows, or at least part of what he knows, about Uncle Frank. This shows that he is developing in the area of honesty. Before, David would have kept all this to himself, rather than face his parents with knowledge he knows will displease them.Through dreadful experiences, David feels an emerging sense of adulthood. David and his parents are not on good terms with David's grandparents because Wes locked Frank in his basement. Julian, David's grandfather, is very unhappy that Wes would lock up his own brother despite the fact that Wes saves Frank the humiliation of going to jail. David faces an even more intimidating threat when he notices that a few of the hired hands from his grandfather's ranch come to his house to try and break Frank free. He comments, These men must have figured, with Grandpa's help, that Frank was in the basement, and that rear door was the way they were going in after him… (1). David is close to being an adult because he realizes how he must act and the gravity of the situation in which he and his family are involved. By now, David has issued forth a sense of development and maturity. He is far from the child who once looked forward to visits from his uncle and visits to his grandfather's ranch. As an adult, he is concerned with the welfare of his family and his parents' well being, emotionally. David exemplifies this and stands by his family when they are in need. He does not desert them or feel shameful. He stays loyal and true to those he cares for and loves. Thus, he has shown his ability to act as an adult would. One can never be too sure when the innocence of childhood is lost, the sure thing is that everyone becomes an adult eventually, and that's when they lose their innocence. In many cases, this change from child to adult is a harsh one, often it is the realization that the world is not perfect. The shootings at Columbine is just one example. Those children were faced with the severe reality that death does not apply only to older people, but to anyone in the world. This revelation caused many of them to cease their immaturity and become an adult. And it was a very difficult task for many of them. One must be careful for corruption rears its ugly head where you least expect it. The loss of innocence signifies a person's metamorphosis from a child to an adult. Therefore, it is the events and happenings in life that trigger this change. Please note that this sample paper on Montana 1948 EssayMaturity is for your review only. In order to eliminate any of the plagiarism issues, it is highly recommended that you do not use it for you own writing purposes. In case you experience difficulties with writing a well structured and accurately composed paper on Montana 1948 EssayMaturity, we are here to assist you. 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Elements of Drama

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Our staff of freelance writers includes over 120 experts proficient in Elements of Drama, therefore you can rest assured that your assignment will be handled by only top rated specialists. Order your Elements of Drama paper at affordable prices!In a rapidly changing world, the purpose and function of the elements of drama are changing. Drama is a reflection of society based upon the human context of roles, relationships and situations. Every form of dramatic activity contains certain elements that are crucial to all drama. These elements are the building blocks of each drama and gives it its own shape and form. Drama allows us to explore the way human beings think, feel and communicate, learning to understand others and ourselves much more fully. Traditional drama such as play texts and improvisation are not the only forms of fictional contexts. The elements of drama are present and alive in many aspects of society. However, developments within society have greatly impacted the nature of drama and have resulted in a transference of the elements of drama. This essay will examine the purpose and function of drama outside of traditional theatre.

Children live in a world of fantasy, a world of endless possibilities. All children have the ability to pretend they are someone else, or pretend they are in a completely different place. This is a crucial part of their development as it is their way of understanding the world. Childs play is by no means new, but has never been formally recognised as drama. These games contain several fundamental elements of drama and are actually a basic form of rehearsed improvisation. When playing these games, children enter into a fictional context made up of roles, relationships and situations. The children adopt roles and begin to form and block a performance. Often, a child will stop the action and change elements of the game he or she is not satisfied with; in doing this the child is actually manipulating the elements of drama. The purpose of drama is to increase our understanding of ourselves and the world. Childs play fulfils this purpose as it allows children to effectively develop their understanding of themselves and the world through the use and manipulation of the elements of drama. Although this activity is highly beneficial for children, it is becoming less common. Society has been forced indoors and children are being raised in front of the television.

The emergence of television has made drama available to everyone in the world. The transference of the elements of drama is clearly evident in the form of reality television. The show Big Brother is an excellent example of this transference as it contains several fundamental elements of drama. When real people are taken out of their natural environment into the world of Big Brother, they are effectively entering into a fictional context. Participants accept this context and assume their role within the game. The shows staff edit the events that take place on a nightly basis; effectively manipulating the elements of drama. Reality television focuses on the human context of relationships and situation. As the participants form bonds, tension of relationship is created. Tension of task is also created each week as participants are set a specific task to achieve. When the shows audience votes off members of the group each week, they are actually entering into the fictional context of the Big Brother world. The process of voting members off the show also creates tension of mystery and surprise, thereby generating focus. The purpose of drama is to increase our understanding of ourselves and the world. Reality television, such as Big Brother fulfils this purpose as it is a true reflection of society and allows the audience to gain a better understanding of human experience.

Advancements in technology has led to the creation of new mediums able to convey drama. Over the past decade, virtual technology has swept the world and has revolutionised the way we perceive entertainment. The transference of the elements of drama is clearly evident in virtual reality. This form of entertainment is based upon the human context of roles, relationships, and situations. Individuals assume a role and enter into the fictional context of the game. Elements of the game such as movement, time, place, mood and language are established and controlled by game designers to create tension and focus. Tension of relationship is created as the central character forms bonds with other characters in the game. In platform games such as Mario and Zelda, tension of task is created as the player is set numerous tasks to achieve as they progress through the story. Tension of mystery and surprise are created as elements of the story are revealed throughout the game. But regardless of these elements, virtual reality can not be considered drama. Whatever the form, the purpose of drama is to increase our understanding of ourselves and the world. At present, virtual reality does not fulfil this purpose as these games convey little meaning and present highly distorted representations of society. Instead, virtual reality merely attempts to satisfy society's basic need for entertainment.

In conclusion, developments within society have greatly impacted the nature of drama and have resulted in a transference of the elements of drama. These elements are the building blocks of drama and give each drama its own unique shape and form. When children play they make use of these elements instinctively as means to develop their understanding of themselves and the world. Although highly beneficial, this activity is becoming less common in our modern society. This transference of the elements is also evident in the form of reality television. Based upon the elements of human context, tension created by the shows participants is heightened and manipulated by the shows staff. The process of voting members off allows the audience to enter the fictional context of reality television. Advancements in technology have led to the creation of fictional contexts within virtual technology. Although this form of entertainment contains several elements of drama, it fails to satisfy the purpose of drama. Virtual technology comes as a result of the demanding nature of modern society and merely attempts to satisfy society's basic need for entertainment. The transference of the elements of drama in our modern society are a direct representation of the changing nature of drama. Drama is a reflection of society and as we continue to advance, the nature of drama will develop accordingly.

Please note that this sample paper on Elements of Drama is for your review only. In order to eliminate any of the plagiarism issues, it is highly recommended that you do not use it for you own writing purposes. In case you experience difficulties with writing a well structured and accurately composed paper on Elements of Drama, we are here to assist you. Your cheap custom college paper on Elements of Drama will be written from scratch, so you do not have to worry about its originality.

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